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Fatigue (physical)

Name of Symptom/Sign:
Fatigue
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ICD-10 R53
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ICD-9 780.7
OMIM {{{OMIM}}}
MedlinePlus {{{MedlinePlus}}}
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DiseasesDB {{{DiseasesDB}}}

Fatigue is a state, following a period of mental or physical activity, characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness, sleepiness, or irritability. It may also follow when, from any cause, energy expenditure outstrips restorative processes and may be confined to a single organ.

Fatigue can also be quite dangerous when performing certain duties that require constant concentration, such as driving a vehicle. When someone is sufficiently fatigued, they may experience microsleepsthat can cause them to lose concentration; however, objective cognitive testing should be done to differentiate the neurocognitive deficits of brain disease from those attributable to tiredness.

The sense of fatigue is believed to originate in the reticular activating systemof the lower brain.

Inhaltsverzeichnis

  • 1 Types
  • 2 Causes
  • 3 See also
  • 4 External links

Types

There are seen to be two main types of fatigue; Central and Peripheral.

  • Central Fatigue is composed of voluntary or involuntary failure of neural drive affecting either the number of MN recruited, or their firing frequency. Causes include nervous damage and inhibition of voluntary effort coming from hard physical work, illness, worry, pain etc.
  • Peripheral Fatigue affects the neuromuscular junction or muscle fibres(Motor units) and all steps in propagation of an action potentialcan be affected.

Causes

It is typically the result of working, mental stress, jet lagor active recreation, but also from boredomor diseaseor simply lack of sleep. It may also have chemical causes, such as poisoningor mineralor vitamin deficiencies.

When chronic (meaning of six months or more duration) it is a symptom of nearly 30 different diseases. Post exertional fatigue, also known as exercise intolerance, is however far more rare, and is primarily found in organic brain diseases, mitochondrial disease, and neuromuscular disease.

This list is incomplete; you can help by expanding it.
  • Chronic fatigue syndrome(CFS)
  • Depression
  • Diabetes
  • Hyperparathyroidism
  • Hypothyroidism
  • Myasthenia gravis
  • Addison's disease
  • Pregnancy
  • Parkinson's disease
  • Anemia
  • Multiple sclerosis
  • Arthritis
  • Certain medications, e.g. lithium salts, ciprofloxacin

See also

  • Combat stress reaction(Battle fatigue)
  • Malaise
  • Asthenia
  • Paresis
  • Debility
  • Muscle weakness
  • Muscle fatigue
  • Infectious mononucleosis

External links

  • NIH/Medline
  • National Cancer Institute
  • International Journal of Fatiguede:Lethargie

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Retrieved from "http://en.wikipedia.org/Fatigue_%28physical%29"



This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Fatigue+%28physical%29 Wikipedia article Fatigue (physical).

 
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