Thermogenesis

Thermogenesis is the process of heatproduction. Non-shivering thermogenesis usually occurs in brown adipose tissue(brown fat) that is present in newborn and hibernating mammalsand in human infants. It is a process where substances such as free fatty acids(derived from triacylglycerols) remove purine (ADP,GDP...) inhibition of thermogenin(uncouping protein-1) which causes an influx of H+ into the matrix of the mitochondriaand bypasses the ATP synthasechannel. This uncouples oxidative phosphorylation and the energy from the proton motive forceis dissipated as heatrather than producing ATP from ADP.

This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Thermogenesis Wikipedia article Thermogenesis.