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Surface epithelial-stromal tumour

**{{{Name|Surface epithelial-stromal tumour}}}**
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}} Surface epithelial-stromal tumours are a class of ovarian neoplasmsthat may be benignor malignant.

Neoplasmsin this group are derived from the ovariansurface epithelium(modified peritoneum) or the epithelial inclusions that are a usual finding in the ovarian cortexof adultwomen.

This group of tumours accounts for 50-55% of all ovarian tumours, and the malignant forms account for approximately 90% of ovarian malignancies in North America.

Serum Ca₁₂₅ is often elevated and can be a useful tumour marker to assess the progress of treatment.

Classification

Epithelial-stromal tumours are classified on the basis of the epithelial celltype, the relative amounts of epithelium and stroma, the presence of papillaryprocesses, and the location of the epithelial elements.

Microscopicpathologicalfeatures determine whether a surface epithelial-stromal tumour is benign, borderline(evidence of malignancy), or malignant(evidence of malignancy and stromal invasion).

This group consists of serous, mucinous, endometrioid, clear cell, and brenner(transitional cell) tumours, though there are a few mixed, undifferentiated and unclassified types.

External links

John Hopkins: "Surface Epithelial Tumors"
Diagram: "Epithelial Stromal Ovarian Tumors"

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