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Squamous cell carcinoma

**{{{Name|Squamous cell carcinoma}}}**
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}} In medicine, squamous cell carcinoma is a form of cancerof the carcinomatype that may occur in many different organs, including the skin, the esophagus, the lungs, and the cervix. It is a malignant tumour of epitheliumthat shows squamous celldifferentiation.

Squamous cell carcinomas account for about 20% of non-melanoma skin cancers, (with basal cell carcinomasaccounting for about 80%), but are clinically more significant because of their ability to metastasize. Squamous cell carcinoma is usually developed in the epithelial layer of the skinand sometimes in different mucous membranes of the body. This type of cancercan be seen on the skin, lips, inside the mouth, throat or esophagus. This type of cancer is characterized by red, scaly skin that becomes an open sore.

When associated with the lung, it often causes ectopic production of parathyroid hormone-related protein(PTHrP), resulting in hypercalcemia.

Squamous cell carcinoma strikes more than 200,000 people in the United Statesalone every year. Smoking is a significant risk factor.

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This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Squamous+cell+carcinoma Wikipedia article Squamous cell carcinoma.

All text is available under the terms of the GNU Free Documentation License