Serous tumour

Serous tumours are part of the surface epithelial-stromal tumourgroup of ovarian neoplasms. They are common neoplasmswith a strong tendency to bilaterality, and they account for 30% of all ovarian tumours. Sixty percent are benign, 10% are borderline and 30% are malignant.

Explanation

Benign serous tumours are unilocular(have one lobe), contain clear fluid and have a smooth lining composed of columnar epithelial cellswith cilia. In borderline lesions, the cyst or surface is lined by papillary structures, which are often very complex. Microscopically, stromal papillae are covered by atypical epithelial cells, but stromal invasion is absent. Malignant serous tumours are solid, may be cystic and often show hemorrhageand necrosis. Serous carcinomas often have bulky peritonealand omentalmetastases, and spread to the lymph nodesis frequent.

Unsurprisingly, 5-year survival decreases as the stage increases. There is a 25% survival ratewith a stage III serous carcinoma.

This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Serous+tumour Wikipedia article Serous tumour.