Granulosa cell tumour
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ICD9 = 183|
ICDO = 8620 |
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Granulosa cell tumours (or granulosa-theca) are part of the sex cord-stromal tumourgroup of ovarian neoplasms.
The peak age at which they occur is 50-55 years, but they may occur at any age.
Inhaltsverzeichnis
- 1 Clinical presentation
- 2 Histology
- 3 See also
- 4 External links
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Clinical presentation
Estrogensare produced by functioning tumours, and the clinical presentation depends on the patient's age.
- If the patient is postmenopausal, she usually presents with abnormal uterine bleeding.
- If the patient is of reproductiveage, she would present with menometrorrhagia.
- If the patient has not undergone puberty, isosexual-pseudo-precocitymay be seen.
Histology
The most characteristic gross appearance is a smooth surfaced solid and cystic lesion with the cysts filled with blood.
Hemoperitoneum is an infrequent but classical presentation.
A large variety of histologicalpresentations exists, but they have two key features:
- Call-Exner bodies(granulosa cellsarranged haphazardly around a space containing eosinophilicfluid); and
- Pale uniform nuclei, often with grooves
See also
- granulosa cell
- Sertoli-Leydig cell tumour
External links
- GPnotebook-46858173
- Photo of tumor
- Slides
- indiandoctors.com
This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Granulosa+cell+tumour Wikipedia article Granulosa cell tumour.
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