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Microalbuminuria

Microalbuminuria - the measurement of small amounts of albuminin the urine that cannot be detected by urine dipstick methods.

Microalbuminuria is diagnosed:

  • excretion of 30?300 mg of albumin/24 h
  • or 20?200 µg/min or 30?300 µg/mg of creatinine on two of three urine collections

Inhaltsverzeichnis

  • 1 Significance
  • 2 References
  • 3 See also
  • 4 External links

Significance

  • an indicator of subclinical cardiovascular disease
  • marker of vascular endothelial dysfunction
  • an important prognostic marker for kidney disease
    • in diabetes mellitus
    • in hypertension
  • increasing microalbuminuria level during the first 48 hours after admission to an intensive care unitpredicts elevated risk for acute respiratory failure, multiple organ failure, and overall mortality

References

  • Abid O, Sun Q, Sugimoto K, et al. Predictive value of microalbuminuria in medical ICU patients. Chest. 2001;120:1984-1988.
  • Lievre M, Marre M, Chatellier G, Plouin P, Reglier J, Richardson L et al. The non-insulin-dependent diabetes, hypertension, microalbuminuria or proteinuria, cardiovascular events, and rampiril (DIABHYCAR) study : design, organization, and patients recruitment. DIABHYCAR Study Group. Controlled Clinical Trials 2000; 21: 383-96.
  • Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators [see comments]. Lancet 2000;355:253-9
  • Andersen S, Blouch K, Bialek J, Deckert M, Parving HH, Myers BD. Glomerular permselectivity in early stages of overt diabetic nephropathy. Kidney International 2000;58: 2129-37
  • Lemley KV, Abdullah I, Myers BD, Meyer TW, Blouch K, Smith WE et al. Evolution of incipient nephropathy in type 2 diabetes mellitus. Kidney International 2000;58:1228-37.
  • Parving HH, Lenher H, Brochner-Mortensen J, Gomis R, Andersen S, Arner P et al The effect of irbesartan on the development of diabetic nephropathy in patients with Type 2 diabetes. [see comments]. New England Journal of Medicine 2001;345:870-8.

See also

  • albuminuria

External links

  • NIH/Medline
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It uses material from the http://en.wikipedia.org/wiki/Microalbuminuria Wikipedia article Microalbuminuria.

 
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