Hypokalemic periodic paralysis
Hypokalemic periodic paralysis is characterized by a fall in potassiumlevels in the blood. In individuals with this mutation attacks often begin in adolescence and are triggered by strenuous exercise or high carbohydratemeals. Weakness may be mild and limited to certain muscle groups, or more severe and affect the arms and legs. Attacks may last for a few hours or persist for several days. Some patients may develop chronic muscle weakness later in life.
Treatment of the periodic paralyses focuses on preventing further attacks and relieving acute symptoms. Avoiding carbohydrate-rich meals and strenuous exercise, and taking acetazolamide daily may prevent hypokalemic attacks. Attacks can be managed by drinking a potassium chloride oral solution.
The prognosis for periodic paralysis varies. Chronic attacks may result in progressive weakness that persists between attacks. Some cases respond well to treatment, which can prevent or reverse progressive muscle weakness
- Hyperkalemic periodic paralysis
- Periodic paralysis
Categories: Channelopathy| Genetic disorders| Medicine stubs
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It uses material from the http://en.wikipedia.org/wiki/Hypokalemic+periodic+paralysis Wikipedia article Hypokalemic periodic paralysis.