Gramicidin A

GramicidinA is a derivative of gramicidin. It is a linear polypeptide, having only fifteen amino acids, and kills the pathogenicaerobicorganisms by spoiling the penetrability of the cell membraneand phosphorylation. Because its molecule has no charged amino acid and the N-end and C-end are blocked, gramicidin A is sparingly soluble in the water (less than 10 mg in a litre), thus requiring some detergents, and in hydrocarbons. The structure of Gramicidin A has been solved using Solid State NMR by Randal R. Ketchem, Weidong Hu and Timothy A. Cross (PubMed Abstract).

See also:

• gramicidin B
• gramicidin C

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It uses material from the http://en.wikipedia.org/wiki/Gramicidin+A Wikipedia article Gramicidin A.