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Liuwei dihuang pill, also known as liuwei dihuang wan (), is a prescription (方剂) in traditional Chinese medicine and pharmacy. In Japanese kampo, it is known as "Rokumi-gan" (六味丸 ろくみがん) (it is also known as Kampo #87). It is commonly made into Chinese patent medicine.
History The formula was created by Qian Yi () as dihuang pill (地黄丸). It was published in "Xiao'er Yao Zheng Zhi Jue" (also known as "Key to Therapeutics of Children's Diseases", "The Correct Execution of Pediatric Medicinals and Patterns" ) in 1119 by Qian Yi's student. [http://home.comcast.net/~piannone/o-s/ch-innerhist.html]The formula was changed slightly when it was borrowed as a Japanese kampo formula. Some Chinese species of herbs were replaced with herbs found in Japan. For example, Alisma plantago-aquatica was replaced with Alisma orientale for zé xiè.
Chinese classic herbal formula
Japanese kampo formula
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