ICD-10 Chapter IV: Endocrine, nutritional and metabolic diseases


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E00-E35 - Endocrine diseases

(E00-E07) Thyroid gland / Thyroid hormone

  • () Congenital iodine-deficiency syndrome
  • () Iodine-deficiency-related thyroid disorders and allied conditions
  • () Iodine-deficiency-related diffuse (endemic) goitre
  • () Iodine-deficiency-related multinodular (endemic) goitre
  • () Iodine-deficiency-related (endemic) goitre, unspecified
  • () Other iodine-deficiency-related thyroid disorders and allied condition
  • () Subclinical iodine-deficiency hypothyroidism
  • () Other hypothyroidism
  • () Congenital hypothyroidism with diffuse goitre
  • () Congenital hypothyroidism without goitre
  • () Hypothyroidism due to medicaments and other exogenous substances
  • () Postinfectious hypothyroidism
  • () Atrophy of thyroid (acquired)
  • () Myxoedema coma
  • () Other nontoxic goitre
  • () Thyrotoxicosis (hyperthyroidism)
  • () Thyrotoxicosis with diffuse goitre
  • Graves' disease
  • () Thyrotoxicosis with toxic single thyroid nodule
  • () Thyrotoxicosis with toxic multinodular goitre
  • () Thyrotoxicosis from ectopic thyroid tissue
  • () Thyrotoxicosis factitia
  • () Thyroid crisis or storm
  • () Other thyrotoxicosis
  • () Thyrotoxicosis, unspecified
  • () Thyroiditis
  • () Acute thyroiditis
  • () Subacute thyroiditis
  • De Quervain's thyroiditis
  • () Chronic thyroiditis with transient thyrotoxicosis
  • () Autoimmune thyroiditis
  • Hashimoto's thyroiditis
  • () Drug-induced thyroiditis
  • () Other chronic thyroiditis
  • Riedel's thyroiditis
  • () Thyroiditis, unspecified
  • () Other disorders of thyroid
  • () Hypersecretion of calcitonin
  • () Dyshormogenetic goitre
  • () Other specified disorders of thyroid
  • Sick-euthyroid syndrome
  • () Disorder of thyroid, unspecified
  • (E10-E16) Pancreas / Insulin, glucagon

    (E10-E14) Diabetes mellitus

  • Note: the following conditions are subtypes of each code from E10-14:
  • (E1x.0) Diabetic coma
  • (E1x.1) Diabetic ketoacidosis
  • (E1x.2) Diabetic nephropathy
  • (E1x.3) Diabetic retinopathy
  • (E1x.4) Diabetic neuropathy
  • (E1x.5) Diabetic angiopathy
  • (E1x.6) Diabetic arthropathy
  • () Insulin-dependent diabetes mellitus
  • () Non-insulin-dependent diabetes mellitus
  • () Malnutrition-related diabetes mellitus
  • () Other specified diabetes mellitus
  • () Unspecified diabetes mellitus
  • (E15-E16) Other disorders of glucose regulation and pancreatic internal secretion

  • () Nondiabetic hypoglycaemic coma
  • Drug-induced insulin coma in nondiabetic
  • Hyperinsulinism with hypoglycaemic coma
  • Hypoglycaemic coma NOS
  • () Other disorders of pancreatic internal secretion
  • () Drug-induced hypoglycaemia without coma
  • () Other hypoglycaemia
  • Functional nonhyperinsulinaemic hypoglycaemia
  • Hyperinsulinism: NOS
  • Hyperinsulinism: functional
  • Hyperplasia of pancreatic islet beta cells NOS
  • Posthypoglycaemic coma encephalopathy
  • () Hypoglycaemia, unspecified
  • () Increased secretion of glucagon
  • () Abnormal secretion of gastrin
  • Hypergastrinaemia
  • Zollinger-Ellison syndrome
  • () Other specified disorders of pancreatic internal secretion
  • () Disorder of pancreatic internal secretion, unspecified
  • (E20-E21) Parathyroid gland / PTH

  • () Hypoparathyroidism
  • () Idiopathic hypoparathyroidism
  • () Pseudohypoparathyroidism
  • () Hyperparathyroidism and other disorders of parathyroid gland
  • () Primary hyperparathyroidism
  • () Secondary hyperparathyroidism, not elsewhere classified
  • (E22-E23) Pituitary gland / ADH, oxytocin, GH, ACTH, TSH, LH, FSH, prolactin

  • () Hyperfunction of pituitary gland
  • () Acromegaly and pituitary gigantism
  • () Hyperprolactinaemia
  • () Syndrome of inappropriate secretion of antidiuretic hormone
  • Central precocious puberty
  • () Hypofunction and other disorders of pituitary gland
  • () Hypopituitarism
  • Fertile eunuch syndrome
  • Hypogonadotropic hypogonadism
  • Idiopathic growth hormone deficiency
  • Isolated deficiency of gonadotropin
  • Isolated deficiency of growth hormone
  • Isolated deficiency of pituitary hormone
  • Kallmann's syndrome
  • Lorain-Levi short stature
  • Necrosis of pituitary gland (postpartum)
  • Panhypopituitarism
  • Pituitary cachexia
  • Pituitary insufficiency NOS
  • Pituitary short stature
  • Sheehan's syndrome
  • Simmonds' disease
  • () Drug-induced hypopituitarism
  • () Diabetes insipidus
  • () Hypothalamic dysfunction, not elsewhere classified
  • () Other disorders of pituitary gland
  • Abscess of pituitary
  • Adiposogenital dystrophy
  • () Disorder of pituitary gland, unspecified
  • (E24-E27) Adrenal gland / Aldosterone, cortisol, epinephrine, norepinephrine

  • () Cushing's syndrome
  • () Pituitary-dependent Cushing's disease
  • () Nelson's syndrome
  • () Ectopic ACTH syndrome
  • () Alcohol-induced pseudo-Cushing's syndrome
  • () Other Cushing's syndrome
  • () Cushing's syndrome, unspecified
  • () Adrenogenital disorders
  • () Congenital adrenogenital disorders associated with enzyme deficiency
  • Congenital adrenal hyperplasia
  • *
  • Congenital adrenal hyperplasia due to 21-hydroxylase deficiency
  • () Hyperaldosteronism
  • () Primary hyperaldosteronism
  • Conn's syndrome
  • Primary aldosteronism due to adrenal hyperplasia (bilateral)
  • () Secondary hyperaldosteronism
  • () Other hyperaldosteronism
  • Bartter's syndrome
  • () Hyperaldosteronism, unspecified
  • () Other disorders of adrenal gland
  • () Other adrenocortical overactivity
  • () Primary adrenocortical insufficiency
  • Addison's disease
  • () Addisonian crisis
  • () Drug-induced adrenocortical insufficiency
  • () Other and unspecified adrenocortical insufficiency
  • Hypoaldosteronism
  • Adrenocortical insufficiency NOS
  • () Adrenomedullary hyperfunction
  • (E28-E30) Gonads / Estrogen, androgens, testosterone, etc.

  • () Ovarian dysfunction
  • () Estrogen excess
  • () Androgen excess
  • () Polycystic ovarian syndrome
  • () Primary ovarian failure
  • Premature menopause NOS
  • () Testicular dysfunction
  • () Testicular hyperfunction
  • () Testicular hypofunction
  • 5-Alpha-reductase deficiency (with male pseudohermaphroditism)
  • Testicular hypogonadism NOS
  • () Disorders of puberty, not elsewhere classified
  • () Delayed puberty
  • () Precocious puberty
  • () Other disorders of puberty
  • Premature thelarche
  • (E31-E35) Other

  • () Polyglandular dysfunction
  • () Autoimmune polyglandular failure
  • Schmidt's syndrome
  • () Polyglandular hyperfunction
  • () Diseases of thymus
  • () Persistent hyperplasia of thymus
  • () Abscess of thymus
  • () Other endocrine disorders
  • () Carcinoid syndrome
  • () Other hypersecretion of intestinal hormones
  • () Ectopic hormone secretion, not elsewhere classified
  • () Short stature, not elsewhere classified
  • NOS
  • constitutional
  • Laron-type
  • psychosocial
  • () Constitutional tall stature
  • Constitutional gigantism
  • () Androgen resistance syndrome
  • Reifenstein's syndrome
  • () Other specified endocrine disorders
  • Progeria
  • () Disorders of endocrine glands in diseases classified elsewhere
  • () Disorders of thyroid gland in diseases classified elsewhere
  • () Disorders of adrenal glands in diseases classified elsewhere
  • () Disorders of other endocrine glands in diseases classified elsewhere
  • E40-68 - Nutritional diseases

    (E40-E46) Malnutrition

  • () Kwashiorkor
  • () Nutritional marasmus
  • () Marasmic kwashiorkor
  • () Unspecified severe protein-energy malnutrition
  • () Protein-energy malnutrition of moderate and mild degree
  • () Retarded development following protein-energy malnutrition
  • () Unspecified protein-energy malnutrition
  • (E50-E64) Other nutritional deficiencies

  • () Vitamin A deficiency
  • () Vitamin A deficiency with conjunctival xerosis
  • () Vitamin A deficiency with Bitot's spot and conjunctival xerosis
  • () Vitamin A deficiency with corneal xerosis
  • () Vitamin A deficiency with corneal ulceration and xerosis
  • () Vitamin A deficiency with keratomalacia
  • () Vitamin A deficiency with night blindness
  • () Vitamin A deficiency with xerophthalmic scars of cornea
  • () Other ocular manifestations of vitamin A deficiency
  • Xerophthalmia NOS
  • () Thiamine deficiency
  • () Beriberi
  • () Wernicke's encephalopathy
  • () Niacin deficiency (pellagra)
  • () Deficiency of other B group vitamins
  • () Riboflavin deficiency
  • Ariboflavinosis
  • () Pyridoxine deficiency
  • () Deficiency of other specified B group vitamins
  • () Ascorbic acid deficiency
  • Scurvy
  • () Vitamin D deficiency
  • () Rickets, active
  • () Other vitamin deficiencies
  • () Deficiency of vitamin E
  • () Deficiency of vitamin K
  • () Dietary calcium deficiency
  • () Dietary selenium deficiency
  • () Dietary zinc deficiency
  • () Deficiency of other nutrient elements
  • () Iron deficiency
  • () Magnesium deficiency
  • () Manganese deficiency
  • () Chromium deficiency
  • () Molybdenum deficiency
  • () Vanadium deficiency
  • () Other nutritional deficiencies
  • () Essential fatty acid (EFA) deficiency
  • () Sequelae of malnutrition and other nutritional deficiencies
  • (E65-E68) Obesity and other hyperalimentation

  • () Localized adiposity
  • Fat pad
  • () Obesity
  • () Obesity due to excess calories
  • () Drug-induced obesity
  • () Extreme obesity with alveolar hypoventilation
  • Pickwickian syndrome
  • () Other obesity
  • Morbid obesity
  • () Obesity, unspecified
  • () Other hyperalimentation
  • () Hypervitaminosis A
  • () Hypercarotenaemia
  • () Megavitamin-B 6 syndrome
  • () Hypervitaminosis D
  • () Sequelae of hyperalimentation
  • E70-E90 - Metabolic diseases

    (E70-E79) Metabolic disorders of proteins, fats, and carbohydrates

    (E70-E72) Amino-acids

  • () Disorders of aromatic amino-acid metabolism
  • () Classical phenylketonuria
  • () Other hyperphenylalaninaemias
  • () Disorders of tyrosine metabolism
  • Alkaptonuria (ILDS E70.210)
  • Ochronosis (ILDS E70.230)
  • Tyrosinaemia
  • () Albinism
  • Chediak-Higashi syndrome
  • Cross syndrome
  • Hermansky-Pudlak syndrome
  • () Other disorders of aromatic amino-acid metabolism
  • Disorders of histidine metabolism
  • Disorders of tryptophan metabolism
  • () Disorder of aromatic amino-acid metabolism, unspecified
  • () Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
  • () Maple-syrup-urine disease
  • () Other disorders of branched-chain amino-acid metabolism
  • Propionic acidemia
  • Methylmalonic acidemia
  • Isovaleric acidemia
  • () Disorder of branched-chain amino-acid metabolism, unspecified
  • () Disorders of fatty-acid metabolism
  • Adrenoleukodystrophy (Addison-Schilder)
  • Muscle carnitine palmityltransferase deficiency
  • () Other disorders of amino-acid metabolism
  • () Disorders of amino-acid transport
  • Cystinuria
  • Cystinosis
  • Hartnup disease
  • Lowe's syndrome
  • () Disorders of sulfur-bearing amino-acid metabolism
  • Cystathioninuria
  • Homocystinuria
  • Methioninaemia
  • Sulfite oxidase deficiency
  • () Disorders of urea cycle metabolism
  • Argininaemia
  • Argininosuccinic aciduria
  • Citrullinaemia
  • Hyperammonaemia
  • () Disorders of lysine and hydroxylysine metabolism
  • Glutaric aciduria
  • Hydroxylysinaemia
  • Hyperlysinaemia
  • () Disorders of ornithine metabolism
  • Ornithinaemia (types I, II)
  • () Disorders of glycine metabolism
  • Hyperhydroxyprolinaemia
  • Hyperprolinaemia (types I, II)
  • Non-ketotic hyperglycinaemia
  • Sarcosinaemia
  • (E73-E74) Carbohydrates

  • () Lactose intolerance
  • () Other disorders of carbohydrate metabolism
  • () Glycogen storage disease
  • Glycogen storage disease type I (von Gierke's disease)
  • Glycogen storage disease type II (Pompe's disease)
  • Glycogen storage disease type III
  • Glycogen storage disease type IV
  • Glycogen storage disease type V (McArdle's disease)
  • () Disorders of fructose metabolism
  • Essential fructosuria
  • Fructose-1,6-diphosphatase deficiency
  • Hereditary fructose intolerance
  • () Disorders of galactose metabolism
  • Galactosaemia
  • Galactokinase deficiency
  • () Other disorders of intestinal carbohydrate absorption
  • Glucose-galactose malabsorption
  • Sucrase deficiency
  • () Disorders of pyruvate metabolism and gluconeogenesis
  • Deficiency of phosphoenolpyruvate carboxykinase
  • Deficiency of pyruvate carboxylase
  • Deficiency of pyruvate dehydrogenase
  • () Other specified disorders of carbohydrate metabolism
  • Essential pentosuria
  • Oxalosis
  • Oxaluria
  • Renal glycosuria
  • () Disorder of carbohydrate metabolism, unspecified
  • (E75) Lipids

  • () Disorders of sphingolipid metabolism and other lipid storage disorders
  • () GM 2 gangliosidosis
  • Sandhoff disease
  • Tay-Sachs disease
  • () Other gangliosidosis
  • GM 1
  • GM 3
  • Mucolipidosis IV
  • () Other sphingolipidosis
  • Gaucher's disease (ILDS E75.220)
  • Niemann-Pick disease (ILDS E75.230)
  • Farber's disease (ILDS E75.240)
  • Fabry's disease (ILDS E75.250)
  • () Sphingolipidosis, unspecified
  • () Neuronal ceroid lipofuscinosis
  • Batten disease (Type 3)
  • Bielschowsky-Jansky disease (Type 2)
  • Kufs disease (Type 4)
  • Spielmeyer-Vogt disease (Type 3)
  • () Other lipid storage disorders
  • Cerebrotendinous cholesterosis (van Bogaert-Scherer-Epstein)
  • Wolman's disease
  • () Lipid storage disorder, unspecified
  • (E76-E78) Combinations

  • () Disorders of glycosaminoglycan metabolism
  • () Mucopolysaccharidosis, type I
  • Hurler syndrome
  • () Mucopolysaccharidosis, type II
  • Hunter syndrome
  • () Other mucopolysaccharidoses
  • Sanfilippo syndrome
  • Morquio syndrome
  • () Disorders of glycoprotein metabolism
  • () Defects in post-translational modification of lysosomal enzymes
  • Mucolipidosis II (I-cell disease)
  • Mucolipidosis III (pseudo-Hurler polydystrophy)
  • () Defects in glycoprotein degradation
  • Aspartylglucosaminuria
  • Fucosidosis
  • Mannosidosis
  • Sialidosis (mucolipidosis I)
  • () Disorders of lipoprotein metabolism and other lipidaemias
  • () Pure hypercholesterolaemia
  • Familial hypercholesterolaemia
  • Fredrickson's hyperlipoproteinaemia, type IIa
  • Hyperbetalipoproteinaemia
  • Hyperlipidaemia, group A
  • Low-density-lipoprotein-type (LDL) hyperlipoproteinaemia
  • () Pure hyperglyceridaemia
  • Endogenous hyperglyceridaemia
  • Fredrickson's hyperlipoproteinaemia, type IV
  • Hyperlipidaemia, group B
  • Hyperprebetalipoproteinaemia
  • Very-low-density-lipoprotein-type (VLDL) hyperlipoproteinaemia
  • () Mixed hyperlipidaemia
  • Broad- or floating-betalipoproteinaemia
  • Fredrickson's hyperlipoproteinaemia, type IIb or III
  • Hyperbetalipoproteinaemia with prebetalipoproteinaemia
  • Hypercholesterolaemia with endogenous hyperglyceridaemia
  • Hyperlipidaemia, group C
  • Tubero-eruptive xanthoma
  • Xanthoma tuberosum
  • () Hyperchylomicronaemia
  • Fredrickson's hyperlipoproteinaemia, type I or V
  • Hyperlipidaemia, group D
  • Mixed hyperglyceridaemia
  • () Other hyperlipidaemia
  • Familial combined hyperlipidaemia
  • () Hyperlipidaemia, unspecified
  • () Lipoprotein deficiency
  • Abetalipoproteinaemia
  • High-density lipoprotein deficiency
  • Hypoalphalipoproteinaemia
  • Hypobetalipoproteinaemia (familial)
  • Lecithin cholesterol acyltransferase deficiency
  • Tangier disease
  • (E79-E90) Other metabolic disorders

  • () Disorders of purine and pyrimidine metabolism
  • () Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
  • () Lesch-Nyhan syndrome
  • () Other disorders of purine and pyrimidine metabolism
  • Hereditary xanthinuria
  • () Disorders of porphyrin and bilirubin metabolism
  • () Hereditary erythropoietic porphyria
  • Erythropoietic protoporphyria (ILDS E80.010)
  • Erythropoietic porphyria, congenital (ILDS E80.020)
  • Gunther's disease (ILDS (ILDS E80.020)
  • Erythropoietic porphyria (ILDS (ILDS E80.030)
  • Erythropoietic coproporphyria (ILDS E80.040)
  • () Porphyria cutanea tarda
  • Sporadic porphyria cutanea tarda (ILDS E80.110)
  • Familial porphyria cutanea tarda (ILDS E80.120)
  • () Other porphyria
  • Acute intermittent porphyria (ILDS E80.210)
  • Hereditary coproporphyria (ILDS E80.222)
  • Variegate porphyria (ILDS E80.230)
  • Chester porphyria (ILDS E80.232)
  • Porphyria, hepatic (ILDS E80.240)
  • Pseudoporphyria (ILDS E80.250)
  • Toxic porphyria (ILDS E80.260)
  • Hepatoerythropoietic porphyria (ILDS E80.282)
  • Porphyria, NOS (ILDS E80.290)
  • () Defects of catalase and peroxidase
  • Acatalasia (Takahara)
  • () Gilbert's syndrome
  • () Crigler-Najjar syndrome
  • () Other disorders of bilirubin metabolism
  • Dubin-Johnson syndrome
  • Rotor's syndrome
  • () Disorder of bilirubin metabolism, unspecified
  • () Disorders of mineral metabolism
  • () Disorders of copper metabolism
  • Wilson's disease
  • Menkes disease
  • () Disorders of iron metabolism
  • Hemochromatosis
  • () Disorders of zinc metabolism
  • Acrodermatitis enteropathica
  • () Disorders of phosphorus metabolism
  • Acid phosphatase deficiency
  • Familial hypophosphataemia
  • Hypophosphatasia
  • Vitamin-D-resistant osteomalacia
  • Vitamin-D-resistant rickets
  • () Disorders of magnesium metabolism
  • Hypermagnesemia
  • Hypomagnesemia
  • () Disorders of calcium metabolism
  • Familial hypocalciuric hypercalcaemia
  • Idiopathic hypercalciuria
  • () Cystic fibrosis
  • () Amyloidosis
  • () Non-neuropathic heredofamilial amyloidosis
  • Familial Mediterranean fever
  • Hereditary amyloid nephropathy
  • () Neuropathic heredofamilial amyloidosis
  • Amyloid polyneuropathy (Portuguese)
  • () Heredofamilial amyloidosis, unspecified
  • () Secondary systemic amyloidosis
  • Haemodialysis-associated amyloidosis
  • () Organ-limited amyloidosis
  • Localized amyloidosis
  • () Other amyloidosis
  • () Amyloidosis, unspecified
  • () Volume depletion
  • Dehydration
  • Hypovolaemia
  • () Other disorders of fluid, electrolyte and acid-base balance
  • () Hyperosmolality and hypernatraemia
  • () Hypo-osmolality and hyponatraemia
  • () Acidosis
  • Respiratory acidosis
  • Metabolic acidosis
  • Lactic acidosis
  • () Alkalosis
  • () Mixed disorder of acid-base balance
  • () Hyperkalaemia
  • () Hypokalaemia
  • () Fluid overload
  • () Other disorders of electrolyte and fluid balance, not elsewhere classified
  • Electrolyte imbalance NOS
  • Hyperchloraemia
  • Hypochloraemia
  • () Other metabolic disorders
  • () Disorders of plasma-protein metabolism, not elsewhere classified
  • Alpha-1-antitrypsin deficiency
  • () Lipodystrophy, not elsewhere classified
  • () Lipomatosis, not elsewhere classified
  • () Postprocedural endocrine and metabolic disorders, not elsewhere classified
  • () Postprocedural hypothyroidism
  • () Postprocedural hypoinsulinaemia
  • () Postprocedural hypoparathyroidism
  • () Postprocedural hypopituitarism
  • () Postprocedural ovarian failure
  • () Postprocedural testicular hypofunction
  • () Postprocedural adrenocortical(-medullary) hypofunction
  • () Nutritional and metabolic disorders in diseases classified elsewhere



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