HLA-DQ9

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HLA-DQ9 (DQ9) is an HLA-DQ split antigens also recognized by DQ3, and is specific to the HLA-DQB1
  • 0303 gene product.
    • =Serology= The serotyping efficiency of DQ9 is poor. The recognition of DQB1
  • 0303 by DQ9 and or DQ3 is poorest, DQ2 which recognizes a different DBB1
  • group recognizes DQB1
  • 0303 as efficiently
    • as DQ3. For this reason DQ9 serotyping is a poor method of typing for transplantation or disease association prediction or study.=Alleles= DQB1
  • 0303 (DQ9) is associated with nasal polyps, gestational diabetes, microscopic polyangiitis (Japanese). Primary linkage is with DRB1
  • 0901-DQB1
  • 0303
    • =Haplotypes=

    DQ9.2

    DQA1
  • 0201:DQB1
  • 0303 is associated with type I psoriasis (vulgaris),

    • DQ9.3

    DQA1
  • 0301:DQB1
  • 0303 maybe associated with juvenile diabetes in the orient.
    • (Chinese) Primary linkage of vitiligo is with DQA1
  • 03-DQB1
  • 0303
    • =References=


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