From Wikipedia, the free encyclopedia
48,XXYY syndrome is a sex chromosome anomaly. It affects one in every 17,000 male births. It was previously considered to be a variation of Klinefelter's syndrome. Common features include tall stature, gynecomastia, truncal obesity, skin ulcers, and a craniofacial dysmorphism described as a "pugilistic" facial appearance.The first published report of a boy with a 48,XXYY karyotype was by Sylfest Muldal and Charles H. Ockey in Manchester, England in 1960. It was found in a 15-year-old mentally challenged boy who had signs of Klinefelter syndrome.
This article is based on an article from Wikipedia, the free encyclopedia and is available under the terms of GNU Free Documentation License.
In the Wikipedia there is a list with all authors of this article available.